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Merge Labs ultrasound BCI taps Caltech’s Mikhail Shapiro

Oct 24, 2025

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Sam Altman’s Merge Labs ultrasound BCI is taking shape with the hire of Caltech engineer Mikhail Shapiro, signaling a noninvasive push in brain-computer interfaces. The startup is courting major funding and positioning Shapiro as a founding leader, according to reporting on the planned launch. The move could redefine how people direct AI tools, especially in work settings.

Merge Labs ultrasound BCI aims for noninvasive control

Moreover, Shapiro’s expertise points to ultrasound as a core technology, rather than surgical implants. That choice matters for safety, adoption, and workplace practicality. Noninvasive systems can be deployed faster and at wider scale, if performance crosses key thresholds.

Furthermore, As The Verge first outlined, Altman tapped Shapiro to help steer the startup’s technical strategy and investor conversations. The profile suggests Merge will prioritize ultrasound for neural imaging and control rather than electrodes in the cortex. This approach contrasts with implant-first efforts, while it still promises direct links between human intent and AI actions. Read the report for context and early details from insider sources at The Verge.

Merge Labs brain interface What Shapiro’s research suggests

Therefore, Mikhail Shapiro runs a renowned lab at Caltech that studies biomolecular engineering and neurotechnology. His group has explored ways to use ultrasound to image and modulate brain activity without opening the skull. That track record aligns with Merge’s hinted direction and raises hopes for practical human-computer interfaces. Companies adopt Merge Labs ultrasound BCI to improve efficiency.

Consequently, Ultrasound can travel through bone and focus on small brain regions. Therefore, it can stimulate or monitor target areas with minimal setup. Researchers are still refining precision, dose, and long-term safety. Nevertheless, peer-reviewed work shows growing promise for short-term modulation and mapping. For background on ultrasound’s potential to affect brain activity, see this overview from the NIH on early human studies at NIH Research Matters. You can also explore Shapiro’s academic portfolio at the Shapiro Lab.

ultrasound brain-computer interface Noninvasive brain interfaces and productivity

As a result, Ultrasound-based interfaces could streamline how people trigger complex AI actions. Hands-free control would reduce friction, particularly in multitasking or accessibility scenarios. Moreover, subtle, real-time confirmation signals could speed up routine decisions without extra clicks or keystrokes.

In addition, Potential workplace uses include rapid text generation approval, instant data labeling, and context switching without a mouse or keyboard. Additionally, field workers could run AI-assisted diagnostics while handling equipment. Designers might iterate faster by nudging models during creative flows. As a result, organizations could see gains in speed, ergonomics, and inclusion. Experts track Merge Labs ultrasound BCI trends closely.

Still, performance must rival existing inputs to be useful. Latency, accuracy, and reliability will determine whether ultrasound interfaces become daily tools. Privacy standards must also evolve before companies trust neural signals alongside enterprise data.

Neuralink brain implant comparison

Additionally, Implant-based systems, like those pursued by Neuralink, target high-fidelity control at the neuron level. They aim for superior bandwidth and precision, which could support rich interaction. However, surgical risk and regulatory hurdles limit near-term workplace adoption. Consequently, noninvasive options may reach productivity use cases sooner, even if they offer less control.

For example, The divergence sets up a clear comparison: implant maximum performance versus external ease and scale. Both paths advance the field and will likely coexist. For an overview of Neuralink’s implant timeline and early milestones, see this neutral report from Reuters. Merge Labs ultrasound BCI transforms operations.

Ultrasound neuromodulation research and limits

For instance, Focused ultrasound has documented effects on neural circuits, yet many parameters remain open. Researchers debate optimal frequencies, pulse patterns, and safe exposure limits. Furthermore, individual differences may affect consistency across users.

Meanwhile, Regulatory science will need robust, longitudinal evidence. Therefore, Merge must validate repeatability, safety, and clinical oversight, even for consumer or enterprise features. Transparent testing will build trust. Independent replication will also anchor claims in reproducible science.

Funding signals and market timing

In contrast, Merge is reportedly raising hundreds of millions of dollars to accelerate development. Capital of that scale suggests a multi-year roadmap and significant hardware R&D. Partnerships with device makers could shorten time to pilot trials in controlled settings. Industry leaders leverage Merge Labs ultrasound BCI.

Even with strong funding, real deployments will likely roll out in steps. Early systems may focus on narrow tasks with measurable benefit. Additionally, software integrations with popular AI productivity suites could provide quick wins. Gradual expansion would then follow as performance improves and safety data accumulates.

Security and reliability considerations

For workplace adoption, reliability matters as much as novelty. Operational failures can halt workflows and erode confidence. Recent events underscore this point. A major AWS outage disrupted millions of users and thousands of organizations, according to a detailed postmortem. Therefore, any BCI that drives AI functions must plan for graceful fallbacks when networks fail or services hang. You can review the outage dynamics in Ars Technica’s report.

Data governance must also keep neural signals compartmentalized. Encryption at rest and in transit is table stakes. Moreover, companies will expect strict controls on model training and retention. Clear consent and auditing will be essential to meet enterprise compliance. Companies adopt Merge Labs ultrasound BCI to improve efficiency.

How this shapes AI in daily work

If Merge delivers a viable external interface, AI assistants could become more ambient and less disruptive. People could accept, refine, or reject model outputs with subtle, low-effort cues. In turn, the boundary between thinking and doing would narrow for routine tasks. That said, employers must avoid overreach. Consent and worker agency should guide adoption from the outset.

Training and ergonomics will influence outcomes. Teams should pilot systems with clear metrics, like task completion time and error rates. Moreover, accessibility-first design can unlock broader gains, not just niche wins. Practical wins will build momentum faster than bold claims.

Outlook

Altman’s recruitment of Shapiro places ultrasound at the center of Merge’s early story. The bet aligns with rising interest in noninvasive brain-computer interfaces for real-world work. Additionally, it answers a practical question facing many organizations: how to harness AI without adding friction. Experts track Merge Labs ultrasound BCI trends closely.

Progress will depend on rigorous science and careful product strategy. As evidence grows, noninvasive brain interfaces could shift AI from click-based assistants to near-thought tools. The next year should clarify timelines, partnerships, and pilot use cases. For now, the hire signals a serious push toward scalable, workplace-ready neurotech, grounded in research and focused on productivity.

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